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Cells make GHB by reduction of succinic semialdehyde by means of succinic semialdehyde reductase (SSR). This enzyme seems to be induced by cAMP levels,[79] this means substances that elevate cAMP, such as forskolin and vinpocetine, may perhaps enhance GHB synthesis and release. Conversely, endogeneous GHB production in those having valproic acid ar